It is necessary to coat the optical multilayer anti-reflection film to improve the quality of optical instruments. The automatic design program of film is made with the principle of two-step design and the orthogonal testing method.The design has proved to be highly satisfactory. It confirms the exceptionally good optical performance and technological stability. As a result, the ordinary coating machine can be used to coat high-quality films.Special mention is given here to the design, the program frame as well as the results of the design.