In order to effectively deal with the disturbance of demand changes in the coordinated production-purchase planning,a method of measuring disturbance was put forward,and a disruption management model of the coordinated production-purchase planning problem,considering the production-purchase plan deviation and the minimum cost was constructed.The problem was solved by designing a method based on the knowledge evolution algorithm.The realization process of the algorithm was illustrated.When disruptions occur,the system can respond quickly to the changes in consumers' demand,and readjust the production plan at once.The disturbance case was simulated,and the results were compared with those of a plan rescheduling to verify the feasibility and effectiveness of the disruption management project.It is found that the disruption management can remarkably reduce the deviation of plan and control the cost.