Bubble characteristics in a micro-channel with obstacles were studied by the gas-liquid two phase lattice Boltzmann method.The effects of surface wettability of the obstacles on the bubble deformation,break-up,and coalescence characteristics were investigated.It is found that the serious deformation of bubbles happens when the obstacles are aerophilic.In this case,bubbles are adsorbed by the obstacles.Therefore the break-up occurs and the mass of the bubbles adsorption by the obstacles depends on the wettability of the obstacles surface.On the other hand,although the serious deformation due to the extrusion of obstacles is observed in the cases of hydrophilic walls,there are still about four grid lattices distance between the bubble and obstacles.As a result,the whole bubble can pass the obstacles.Moreover,the deformation of the bubbles becomes more significant with the stronger aerophily of the obstacles surface.