The selection and research of high performance catalyst is the key to producing high value-added syngas from biodiesel by-product glycerol and CO₂ dry reforming. CoFe/CeO₂ catalyst was prepared by colloidal solution combustion method, and the catalytic activity and stability of dry reforming of CO₂ and glycerol were studied in a fixed-bed reactor at a temperature range of 650～800 ℃. The results showed that the CoFe/CeO₂ catalyst prepared by the colloidal solution combustion method had a typical mesoporous structure with a specific surface area of 33.4～40.8 m²/g, showing a strong interaction between the active component Co-Fe and the support CeO₂. 7CoFeCe showed good catalytic performance for dry reforming. The conversion of glycerol at 750 ℃ was 84.8%, and the CO₂ conversion was 19.9%. The CO₂ conversion increased with the increase in temperature, and the maximum conversion of CO₂ at 800 ℃ was 30.3%. It showed that the high temperature was conducive to the reverse water gas shift reaction. The stability experiment showed that the mesoporous CoFe/CeO₂ catalyst had good dry reforming stability.